As an image, Nene appears here and there on the Newgrounds website, like other Pico series characters. She is also featured in a number of other games and movies, including Newgrounds Rumble, Pico Sim Date, and Pico vs. In other movies, she is shown wielding knives to fight enemies, especially in House of 1000 Cats and Pico vs.
In Pico's School, she begs Pico to end her life, which the player may or may not do. She is often known for her flirtatious attitude and her suicidal tendencies, usually prompted by an outbreak of herpes. She is an Asian girl who first appeared in Nene Interactive Suicide in 1999. Pico as he appeared on the old Newgrounds rating system.
Pico is also hot-headed, often acting out in aggression. His weapons of choice are automatic weapons such as the MAC-10, UZI or the M16 Assault Rifle. He also has tremendous skill in unarmed combat, seen in media such as Newgrounds Rumble and Pico's Unloaded. He is an exceptional gunman and is usually seen dual wielding his weaponry. He has white sclera with no pupils as a stylistic choice used throughout his series. Pico is a young man with light skin, ginger hair, beige pants, a green shirt with darker green sleves and red shoes with orange marks.
